Bone Research Society

School of Applied Sciences
University of Brighton
lbourne3@rvc.ac.uk
07926090711
Cockcroft building, Lewes Road, Moulsecoomb, Brighton, BN2 4GJ, UK.

BRS Non-Clinical New Investigator

I am currently an MRC funded Postdoctoral Research Fellow, working under the supervision of Dr Katherine Staines. My research interests lie within the musculoskeletal field and I am working on a number of projects in this area to understand how both bone and cartilage develop, function and undergo pathologies.

Some of these projects include:

- Identifying imaging biomarkers and assessing bone shape changes associated with osteoarthritis
- Understanding how prenatal exposure to alcohol affects the skeleton later in life
- Using RNAseq to idenitfy genes and pathways involved in physiological and injurious hydrstatic pressure on different cartilage models
- Generating a double conditional knockout model to identify the roles of 2 phosphtases (alkaline phosphatase and Phospho1) specifically in the skeleton, to further understand how mineralisation occurs in this tissue

My previous experience and interests included understanding the differences between physiological and pathological mineralisation, for example within bone and during diseases such as vascular calcification.

Research profile: Basic

Other Societies: ORS.