Bone Research Society

Bringing basic and clinical researchers together since 1950

Past BRS Meetings

BRS BRS Annual Meeting 2021

28-30 June 2021, Virtual Meeting

Given the uncertainties for 2021, this year we planned a virtual 3-day meeting from Monday 28th to Wednesday 30th June 2021. The programme was delivered on the zoom platform to ensure reliability. It was a mix of live presentations from international and national experts across a range of research areas bringing together basic and clinical science. There was also a focus on presentations from abstract submissions with interesting question and answer sessions.

Thank you to all our colleagues and speakers who attended.

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BRS BRS Virtual Seminars - Adam Pickard, Joan Chang & Richa Garva (Karl Kadler Group)

27 April 2021, 14:00, Virtual Seminar

Adam Pickard "A non-canonical secretory route for collagen assembly".
Adam is a senior postdoc in Karl Kadler’s lab (Wellcome Centre for Cell-Matrix Research, University of Manchester) studying how cells assemble a collagen-rich extracellular matrix. Published findings from our lab show that cells assemble collagen fibrils under circadian clock control, and that disruption of the clock produces abnormal fibrils that accumulate in numbers. However, earlier work published in 2004 from the Kadler group showed that cells in vivo can secrete procollagen within minutes. My recent work has focused on reconciling these apparently contradictory observations. In his talk, Adam will explain how he has used CRISPR-Cas9 editing and cell culture models to identify a non-classical secretory pathway of collagen secretion. His work has identified an unexpected role of lysosomal compartments in collagen secretion. These observations have relevance to fibrosis, in which uncontrolled deposition of collagen leads can cause death. He with new approaches, using nanoluciferase, to screen for collagen modulatory compounds.

Joan Chang “Understanding the role of endosomal recycling in collagen-I fibril formation”
Joan received her PhD in cancer studies from the lab of Janine Erler (Institute of Cancer Research, University of London), then went on to study adipocytes in the tumour microenvironment at UNC Chapel Hill with Dr Andrew Dudley. In 2016 Joan moved to Karl Kadler's lab where she made discoveries concerning the circadian regulation of collagen fibril assembly. Her recent work is showing that a crucial step in this process is uptake of collagen via the endosomal system. In her talk, Joan will show her recent data on endosomal trafficking using mass spectrometry and a novel method of fluorescence activated sorting of transport vesicles.

Richa Garva “To understand the role of type I collagen in determining cell fate, with translational opportunities for osteoarthritis"
Like Adam and Joan, Richa is a senior postdoc in Karl's lab. Richa approached the question of the purpose of the circadian collagen seen in adult mouse tendon by preforming a conditional knockout of col1a1 by crossing Col1a2CreERT2 and Col1a1-floxed mice, and feeding tamoxifen postnatally. To her surprise, fibroblasts that cannot synthesise col1a1 (and therefore cannot make collagen-I) switch to making collagen-II and express other chondrogenic markers including aggrecan, Sox9 etc. These data hint at a new role for Col1a1 in determining cell fate, and open up potential strategies for treating osteoarthritis.

zoom.us/j/99418943861

Part of BRS Virtual Seminars

BRS BRS Virtual Seminar - Prof van Martin & Dr Andres Garcia-Garcia. University of Basel.

30 March 2021, 14:00, Virtual Seminar

Professor Ivan Martin: Re-engineering developmental processes for bone regeneration

The presentation will exemplify in the context of the recapitulation and regulation of endochondral ossification the general paradigm to enhance robustness in regeneration by engineering developmentally inspired processes. The work will also outline a new class of materials, based on engineered extracellular matrices, capable to deliver the required signals to activate such processes.


Dr Andres Garcia-Garcia: Engineered bone marrow niches to model human hematopoiesis

The presentation will describe a bioreactor-based 3D perfusion culture model enabling the engineering of stromal tissues, possibly including vascular elements. The system has been used to maintain/expand human healthy and malignant hematopoietic stem&progenitor cells, as well as their interactions and compartmentalization.

zoom.us/j/94504735837

Part of BRS Virtual Seminars

BRS Online BRS Clinical Training Course: Osteoporosis and Other Metabolic Bone Diseases 2021

22 March - 19 April 2021, Virtual Sessions Update

Given the uncertainties for 2021, the clinical training course will now be run virtually as a series of live and pre-recorded sessions. More information about the dates of the sessions, programme and registration is now available.

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BRS BRS Virtual Seminars - Claudia Mazzà & Erica Montefiori, University of Sheffield.

23 February 2021, 14:00, Virtual Seminar

Musckuloskeletal modelling of forces transmitted to the joints during walking and the anatomical properties involved.

zoom.us/j/93461584673?pwd=eXk…

Part of BRS Virtual Seminars

BRS BRS Virtual Seminars - Katherine Staines & Rachel Lopera-Burgueno

26 January 2021, 14:00, Virtual Seminar

Katherine Staines: Understanding growth plate fusion mechanisms
As growth slows and eventually ceases, the human growth plate narrows and bone bridges form to span its width. I will describe methods we have developed to understand these processes and how these may predict musculoskeletal health in later life.

KS completed her PhD at the Roslin Institute in 2012 with Colin Farquharson before completing postdoctoral positions with Colin and Andy Pitsillides. She was awarded a Vice Chancellor’s Fellowship at Edinburgh Napier in 2017 before taking a Senior Lectureship position in Brighton at the start of 2020.

Rachel Lopera-Burgueno: The role of regulatory T-cells in osteoarthritis
RLB is a 3rd year PhD student in KS lab also supervised by Graham Wright at Edinburgh Napier University working on the role of regulatory T cells in OA.

The webinar will take place on Tuesday 26th January at 14:00. Join us at https://zoom.us/j/93621652894.

Watch the video

Part of BRS Virtual Seminars

BRS BRS Virtual Seminars - Dr James Edwards and Dr Beatriz Gamez Molina

24 November 2020, Virtual

Dr James Edwards (University of Oxford): "Biometals in Bone Regeneration - Supporting Structure and Stimulating Cells"

Dr Beatriz Gamez Molina (University of Oxford) "The role of dietary cholesterol in myeloma pathogenesis"

Join us here: https://zoom.us/j/98071153308

Watch the video

Part of BRS Virtual Seminars

BRS BRS Virtual Seminars - Stuart Ralston & Beatriz Larraz Prieto

26 October 2020, Online

Stuart Ralston (Edinburgh) on the TOPAZ trial.
Beatriz Larraz Prieto (Edinburgh) on CXCR4 and teriparatide in osteoporosis.

Join us here: https://zoom.us/j/92573181699.

Watch the video

Part of BRS Virtual Seminars

BRS BRS2020 Online

6-8 July 2020

Welcome to BRS 2020 Online. We’ve been through unprecedented times over the last few months and like many other meetings, BRS2020 in Manchester has had to be postponed. But that hasn’t stopped our community continuing to produce high quality science and connecting with each other to exchange ideas and knowledge.

BRS2020 Online will be a platform for this, focussing on the oral communications and posters and we will also have online satellite symposia from our Industry partners and we will also hold the Rare Bone Disease workshop on the Monday evening. We will be holding sessions over the course of the 3 days from 6 - 8 July 2020

boneresearchsociety.org/meeti…

BRS Basic course in bone and cartilage biology and disease - 21-22 November 2019

21-22 November 2019, INOX Conference Suite, University of Sheffield

New to the field of bone and joint? Wanting to catch up on the latest in bone and joint diseases? Organised by the Bone Research Society this 2 day course is for all basic and clinical postgraduate students, postdocs and research fellows who may be starting out in this field, or who want to catch up in preparation for their postgraduate viva.

Programme: https://boneresearchsociety.org/do…

Places are limited and awarded on a first-come-basis. Early booking is therefore recommended to avoid disappointment: 7 November 2019

onlineshop.shef.ac.uk/product…

BRS 5th BRS/BORS Joint Meeting

4-6 September 2019, Cardiff

ASBMR is pleased to announce the availability of funding for two (2) Young Investigator Awards ($1,500 each) to enable attendance and presentation of research at the 5th joint meeting of the Bone Research Society and British Orthopaedic Research Society, Cardiff, UK, September 4th - 6th 2019. If you are interested in applying for this funding please access conference details and submit an abstract on the BRS Annual Meeting Website. Please also email the conference organiser - Luan Barlow, Hg3 Conferences Ltd, at luan.barlow@hg3.co.uk - to register your interest in one of these awards. The abstract deadline is Friday, July 5th, 2019.

boneresearchsociety.org/meeti…

BRS BRS Clinical training course: Osteoporosis and Other Metabolic Bone Diseases

18-20 March 2019, Merton College, Oxford, UK

This three-day residential training course aims to provide trainees in medical specialties such as rheumatology, endocrinology, care of the elderly, gastroenterology, orthopaedics, respiratory medicine and clinical chemistry with the knowledge and understanding to manage patients with osteoporosis and other metabolic bone diseases. The course is intended to focus on practical issues relating to patient management and is strongly recommended for any trainee who foresees that patients with these disorders will form a significant part of their workload in future. A stimulating interactive format will be employed combining lectures, panel discussions, debates and workshops. Specialist nurses in osteoporosis and falls will also find this course valuable, as well as newly qualified consultants or others wishing to update their knowledge in this field.

boneresearchsociety.org/meeti…

BRS Training Day for Primary Care Practitioners: Osteoporosis and Metabolic Bone Diseases

12 September 2018, Birmingham, UK

This one-day training course aims to help GPs and other primary care practitioners to better manage patients with metabolic bone disease. Taking into account the restrictions of primary care and the 10 minute consultation, the course will focus on providing practical and actionable information.

The course has been approved for 6 CPD credits by the Royal College of Physicians (course code 118523).

On completion of the course, it is expected that participants will be able to:

- Assess and investigate metabolic bone diseases in primary care
- Identify when a referral to secondary care is appropriate for further management
- Understand and use latest available guidelines in metabolic bone diseases
- Confidently apply, evaluate and modify primary care treatment in response to the changing needs of the patient

Topics will cover the diagnosis and treatment of osteoporosis and other metabolic bone diseases, including:

- Raised calcium/hyperparathyroidism
- Raised alkaline phosphatase/Paget's disease
- Fracture risk assessment
- Duration of treatment and drug holidays in osteoporosis
- Calcium supplements – do we need them?
- Osteogenesis imperfecta
- Renal bone disease/osteodystrophy
- Falls
- Rickets

Organised by Dr Richard Keen and Dr Judith Bubbear of the Royal National Orthopaedic Hospital, London, the course will be delivered by a faculty of topic experts.

boneresearchsociety.org/meeti…

BRS Bone Research Society Annual Meeting

27-29 June 2018, Winchester, UK

The 2018 Bone Research Society Annual Meeting will take place in the historic city of Winchester, on the King Alfred Campus of the University of Winchester.

The local organisers - Claire Clarkin, Cyrus Cooper, Nick Harvey, Richard Oreffo and Kate Ward are already hard at work putting together an exciting scientific programme and we hope you will be a part of it.

boneresearchsociety.org/meeti…

BRS BRS Clinical Training Course: Osteoporosis and Other Metabolic Bone Diseases

26-28 March 2018, Merton College, Oxford, UK

This three-day residential training course aims to provide trainees in medical specialties such as rheumatology, endocrinology, care of the elderly, gastroenterology, orthopaedics, respiratory medicine and clinical chemistry with the knowledge and understanding to manage patients with osteoporosis and other metabolic bone diseases. The course is intended to focus on practical issues relating to patient management and is strongly recommended for any trainee who foresees that patients with these disorders will form a significant part of their workload in future. A stimulating interactive format will be employed combining lectures, panel discussions, debates and workshops. Specialist nurses in osteoporosis and falls will also find this course valuable, as well as newly qualified consultants or others wishing to update their knowledge in this field.

boneresearchsociety.org/meeti…

BRS Bone Research Society Annual Meeting

25-27 June 2017, Bristol, UK

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BRS Bone Research Society Clinical Training Course: Osteoporosis and other Metabolic Bone Diseases

3-5 April 2017, Merton College, Oxford, UK

This three-day residential training course aims to provide trainees in medical specialties such as rheumatology, endocrinology, care of the elderly, gastroenterology, orthopaedics, respiratory medicine and clinical chemistry with the knowledge and understanding to manage patients with osteoporosis and other metabolic bone diseases. The course is intended to focus on practical issues relating to patient management and is strongly recommended for any trainee who foresees that patients with these disorders will form a significant part of their workload in future. A stimulating interactive format will be employed combining lectures, panel discussions, debates and workshops. Specialist nurses in osteoporosis and falls will also find this course valuable, as well as newly qualified consultants or others wishing to update their knowledge in this field.

boneresearchsociety.org/meeti…

BRS BRS Annual Meeting 2016

29 June - 1 July 2016, Liverpool, UK

Off to Liverpool for the 2016 meeting, for the first time since - well, does anyone know? Certainly for the first time in the Society's current incarnation as the Bone Research Society.

boneresearchsociety.org/meeti…

BRS BRS Training Course: Osteoporosis and Other Metabolic Bone Diseases

16-18 March 2016, St Anne's College, Oxford, UK

This three-day residential training course aims to provide trainees in medical specialties such as rheumatology, endocrinology, care of the elderly, gastroenterology, orthopaedics, respiratory medicine and clinical chemistry with the knowledge and understanding to manage patients with osteoporosis and other metabolic bone diseases. The course is intended to focus on practical issues relating to patient management and is strongly recommended for any trainee who foresees that patients with these disorders will form a significant part of their workload in future. A stimulating interactive format will be employed combining lectures, panel discussions, debates and workshops. Specialist nurses in osteoporosis and falls will also find this course valuable, as well as newly qualified consultants or others wishing to update their knowledge in this field.

Some comments from those who attended the previous course:

“Fantastic course, probably the best I have ever been on”
“Brilliant course set at the right level, knowledgeable speakers, will definitely recommend it”
“Excellent, relevant course – I have already started recommending it to my peers”
“I am really impressed by the speakers, very good learning environment, excellent organisation of the course events”
“Very useful, inspiring course … represented great value for money in terms of both quality and quantity of teaching … I will certainly be recommending this course”

boneresearchsociety.org/meeti…

BRS BRS Annual Meeting 2015 (Jointly with the British Society for Matrix Biology)

1-3 September 2015, Edinburgh, UK

boneresearchsociety.org/meeti…

BRS BRS Training Course: Osteoporosis and Other Metabolic Bone Diseases

13-15 April 2015, Oxford, UK

This three-day residential training course aims to provide trainees in medical specialties such as rheumatology, endocrinology, care of the elderly, gastroenterology, orthopaedics, respiratory medicine and clinical chemistry with the knowledge and understanding to manage patients with osteoporosis and other metabolic bone diseases. The course is intended to focus on practical issues relating to patient management and is strongly recommended for any trainee who foresees that patients with these disorders will form a significant part of their workload in future. A stimulating interactive format will be employed combining lectures, panel discussions, debates and workshops. Specialist nurses in osteoporosis and falls will also find this course valuable, as well as newly qualified consultants or others wishing to update their knowledge in this field.

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BRS BRS Annual Meeting 2014

25-26 June 2014, Sheffield, UK


boneresearchsociety.org/meeti…

BRS BRS Training Course: Osteoporosis and Other Metabolic Bone Diseases

19-21 March 2014, Oxford, UK

boneresearchsociety.org/meeti…

BRS BRS Annual Meeting 2013 (Jointly with British Orthopaedic Research Society)

3-5 September 2013, Oxford, UK

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BRS 2nd New Investigator Workshop

22-23 July 2013, Sheffield, UK

boneresearchsociety.org/downl…

BRS BRS Training Course: Osteoporosis and Other Metabolic Bone Diseases

20-22 March 2013, Oxford, UK

BRS BRS Annual Meeting 2012 (part of Osteoporosis and Bone Conference 2012, Jointly with National Osteoporosis Society and National Association for the Relief of Paget’s Disease)

1-4 July 2012, Manchester, UK

boneresearchsociety.org/meeti…

BRS BRS Training Course: Osteoporosis and Other Metabolic Bone Diseases

26-28 March 2012, Oxford, UK

BRS BRS Annual Meeting 2011 (Jointly with British Orthopaedic Research Society)

27-29 June 2011, Cambridge, UK

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BRS BRS Annual Meeting 2010 (Jointly with European Calcified Tissue Society)

26-30 June 2010, Glasgow, UK

www.ectsoc.org/glasgow2010/in…

BRS BRS Annual Meeting 2009 (Jointly with British Society for Matrix Biology)

14-16 June 2009, London, UK

boneresearchsociety.org/meeti…

BRS BRS Annual Meeting 2008 (Jointly with British Orthopaedic Research Society)

23-25 June 2008, Manchester, UK

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BRS BRS Annual Meeting 2007

3-5 July 2007, Aberdeen, UK

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BRS BRS Annual Meeting 2006 (Jointly with British Orthopaedic Research Society)

5-6 July 2006, Southampton, UK

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BRS BRS Annual Meeting 2005

4-5 July 2005, Birmingham, UK

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BRS BRS Annual Meeting 2004

29-30 June 2004, Oxford, UK

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BRS BRS Annual Meeting 2003

9-11 July 2003, Sheffield, UK

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BRS BRS Annual Meeting 2002

24-26 June 2002, Cardiff, UK

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BRS BRS Annual Meeting 2001

4-5 July 2001, Warwick, UK

boneresearchsociety.org/meeti…

BRS BRS Annual Meeting 2000

10-12 July 2000, Cambridge, UK

boneresearchsociety.org/meeti…

BRS BRS Annual Meeting 1999

22-24 June 1999, Bristol

boneresearchsociety.org/meeti…

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Amy Naylor
Meet the Committee

Amy Naylor
University of Birmingham
Non-clinical ordinary member

BRS Annual Meeting 2022
BRS Annual Meeting 2022

6-8 July 2022, Manchester Metropolitan University, Manchester, UK